Blastocyst Culture And Transfer

How do we maximize IVF success rate?

Blastocyst culture and transfer is a technique which has proven to be a significant step in maximizing the pregnancy rate and keeping the chances of multiple pregnancies low. When the fertilization through IVF is successful, the embryo culture is kept under observation. The Blastocyst culture refers to the process of growing the embryo culture for a period of 5 to 6 days. This helps in determining which embryo is best suitable for implantation and pregnancy. The traditional approach was to keep the embryo for a period of 3 days. The new technique recommends keeping it for 5-6 days to determine the’ best candidate’. This technique of blastocyst transfer is used in IVF.

Blastocyst transfer makes it easy to select the best blastocyst out of which one or two can be implanted into the mother’s womb. This leads to minimizing the chances of multiple births. Thus, Clinical blastocyst culture and transfer occupy an important place in ensuring the success rate and eliminating the chances of multiple pregnancies. IVF treatment has benefitted from the use of this technique.


Blastocyst culture and transfer

It is a modern approach to the traditional method of transferring the embryo to the uterus on the second or the third day of development after IVF. In the traditional approach , the culture could not be maintained beyond two to three days and the implantation had to be done after that period. With the advancement of technique, it is now possible to keep the culture for 5-6 days. It is a known fact that if an embryo survives till this time, it can be determined that the embryo is robust and healthy.

Advantages of ivf with blastocyst culture and transfer

  • It maximizes the chances of selecting the fittest embryos. Fertilization is not a big deal but few embryos are able to survive beyond a day or two. A culture of 5-6 days easily determines which ones are the most likely to survive.
  • It helps in ensuring greater chances of implantation.
  • It helps in minimizing the chances of multiple pregnancies, which is again a hassle for the mother and the doctor.
  • It presents more opportunities for cryopreservation and Frozen embryo transfer technique. The unused embryos can be frozen for use in future. They may be used for the same couple or for donation.

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    Is the procedure suitable for everybody?

    Unfortunately ,not. If the patient has few oocytes, fewer of them will fertilize. In such cases, the blastocyst culture will not be of much help since there will not be many options for selection.

    One should remember that blastocyst culture media does not enhance the health or the survival chances of the embryo. It rather helps in allowing the sustained growth of embryos so that they reach their maximum survival capability.